Kilika is an island off the southern coast of the Spira mainland and the first stop on Yuna's pilgrimage. It can only be reached by boat or airship. The island consists of a small port and village, a large jungle and a Temple of Yevon. It is famous for being the home of High Summoner Ohalland and the Kilika Beasts, the local blitzball team.

The City of Luca is a port at the southern tip of Spira's main continent in Final Fantasy X and Final Fantasy X-2. Luca houses Spira's only Blitzball stadium, and is the home of the Luca Goers, the best team in the league.

Mi'ihen Highroad is a road between the city of Luca and Mushroom Rock, found in Final Fantasy X and Final Fantasy X-2. It was named for Lord Mi'ihen, the founder of the Crusaders, then called the Crimson Blades, who walked down the old path on his way to Bevelle to answer the challenge that his group was a threat to Yevon. It is called a Highroad because of both it's altitude in relation to Luca, and the fact that Mi'ihen walked the "Highroad" when he decided to face the Maesters of Yevon instead of antagonizing them.

Mushroom Rock is a road and mountain formation situated between Djose and Mi'ihen Highroad in Final Fantasy X and Final Fantasy X-2. The area is chiefly known as the site of the ill-fated Operation Mi'ihen where the Crusaders and the Al Bhed joined together to try and defeat Sin. After Yuna and her guardians are branded traitors to Yevon, three summoners can be found wandering the road near the turn-off to the Ravine Path.

Djose is a region of the main continent of Spira in Final Fantasy X and Final Fantasy X-2. It is primarily a Highroad running between the area of Mushroom Rock and the Moonflow. At the junction before entering the Moonflow road, a short path leads the way to Djose Temple, the only notable feature in the area.

The Moonflow is a large river that dissects Spira's main continent into Southern and Northern halves. The primary method of crossing is on Shoopuf, an elephant-like creature that can swim across the expansive river. Moonlillies grow on the banks of the Moonflow and pyreflies gather at night, making the water glow and sparkle, truly a wondrous sight to behold.

Guadosalam is the city of the Guado, and gateway to the Farplane in Final Fantasy X and Final Fantasy X-2. The city sits on the path from the north bank of the Moonflow and the southern trail of the Thunder Plains. It comprises three levels with the exits at the bottom most points, the path to the Farplane on the upper level and the Palace, residence of the current leader, at the center.

In the world of Final Fantasy X, the Farplane is a gathering place for the dead. They come here either after they have been sent or after they die (if they accepted death before they died). If the spirits are not sent to the Farplane, they remain as the Unsent and begin to envy the living, which then turns into hatred; thus they will eventually become fiends. The Farplane can be visited by the living, through an entrance at Guadosalam. The Pyreflies react to their memories to conjure an image of the dead person. However, if you think of a person still living, they will not be shown. The Farplane still is not completely understood by the inhabitants of Spira. The Guado are the keepers of the Farplane; as a result, they have the ability to sense the unsent.

The Thunder Plains, also known as the Gandof Thunder Plains, is a long open barren landscape, which connects Guadosalam to Macalania Woods. It is constantly bombarded by lightning and thunder. Long ago, the plains were a travellers nightmare, until an Al Bhed named Bilghen set up several towers to serve as Lightning Rods, after a suggestion by summoner Gandof. He was in the process of setting up the final tower when he was struck by lightning and killed.

Macalania is a geographical area of Spira in Final Fantasy X. Macalania is comprised of a vast forest filled with beautiful springs and campsites; a frozen Lake, where one of Rin's Travel Agencies can be found; and a magnificent ice palace: Macalania Temple which sits atop the frozen waters.

Bevelle is a city in the game Final Fantasy X and Final Fantasy X-2. It is the capital of Spira and also the base of operations of the Yevon religion and then New Yevon party. It was Yuna's hometown where she was born and lived until the day her father defeated Sin.

Mount Gagazet is the home of the Ronso and gateway to the Holy City of Zanarkand in the world of Spira. The snow-covered, towering Mount Gagazet is considered sacred land by all races of Spira. Only Summoners and their Guardians are permitted to pass beyond the mountain gate as it is the final test the Summoners resolve before entering the Zanarkand Ruins.